He lived in Galicia since he was six, where he carried out his artistic and teaching activity (he was a Professor of Drawing and Calligraphy).
José Seijo created and extensive work that can be found in several museums and private collections. El mar siempre azul, Fiesta de muradanas, O cego de Santa Margarita, Na porta da Casa and Calle de Damas are some of his most important works.
He was awarded the second medal at the Spanish-French Exhibition in Zaragoza (1908) and the third medal at the National Exhibition of Fine Arts (1926) for his work La marisma. He was a member of St Fernando Academy of Fine Arts, the Galician Academy and Nuestra Señora del Rosario Academy of Fine Arts. He was a honourable member and president of the Association of Artists in A Coruña.